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Title

Advances in Protein Chemistry and Structural Biology : Structural Genomics, Part A.

Author
Series
  • (CKB)1000000000701787
Other titles
  • Structural genomics
  • Advances in Protein Chemistry and Structural Biology
  • Structural Genomics, Part A
  • Advances in Protein Chemistry and Structural Biology, Volume 75C
  • Structural Genomics, Part A, Volume 75C
Published
  • Burlington : Elsevier Science 2011
Physical description
1 online resource (170 p.)
ISBN
  • 1282287389
  • 9786612287381
  • 0080922325
  • 0123744369
Notes
  • Description based upon print version of record.
  • English
Contents
  • Front Cover; Advances in Protein Chemistry and Structural Biology; Copyright Page; Contents; Chapter 1: Target Selection in Structural Genomics Projects to Increase Knowledge of Protein Structure and Function Space; I. Background; VI. Summary; Chapter 2: Development of Key Technologies For High-Throughput Cell-Free Protein Production With The Extract From Wheat Embryos; II. Development of the Wheat Cell-Free Translation System; V. Quality of the Protein Products; VI. Isotope and Heavy Atom Labeling; VII. ldquoDifficultrdquo Proteins; VIII. Issues Left Unsolved
  • Chapter 3: High-Throughput Protein Purification for X-Ray Crystallography and NMRI. Introduction; II. Protein Constructs and Expression; III. Purification; Acknowledgments; Chapter 4: Predicting and Characterizing Protein Functions Through Matching Geometric and Evolutionary Patterns of Binding Surfaces; IX. Summary and Conclusion; Acknowledgments; References; Author Index; Subject Index; Color Plate Section
Summary
  • Structural genomics is the systematic determination of 3-dimensional structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome.While most structural biologists pursue structures of individual proteins or protein gr
  • Structural genomics is the systematic determination of 3-dimensional structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome. While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large-scale cloning, expression and purification. One main advantage of this approach is economy of scale.
Subject
Genre
  • Electronic books.
  • text
Language
  • English
Internet Resources
Direct Link
https://copac.jisc.ac.uk/id/44789019?style=html&title=Advances%20in%20Protein%20Chemistry%20and%20Structural%20BiologyStructural
Format
  • Online

Held At

  1. Manchester University Online Information about Manchester University

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